Canagliflozine is an inhibitor of the transport protein of the Glucose Subtype 2 (SGLT2) responsible in 90% of the reabsorption of glucose by the kidneys.The collide of glucose reabsorption causes it to be eliminated through urine.Canagliflozine is used in type 2 diabetes in monotherapy or associated with other hypoglycemianes.
For what conditions or diseases this medication is prescribed?
Canagliflozine is used together with diet and exercise, and sometimes with other medications, to reduce blood sugar levels in patients with type 2 diabetes (a condition in which blood sugar is too high because the body does not produceor does not use insulin in a normal way).Canagliflozine belongs to a class of medications called co-transporter 2 sodium-glucose (SGLT2).Reduce blood sugar by making the kidneys release more glucose in the urine.Canagaglyzine is not used to treat type 1 diabetes (a condition in which the body does not produce insulin and, therefore, cannot control the amount of blood sugar) or diabetic ketoacidosis (a serious condition that can be developedif hyperglycemia is not treated).
Over time, people who have high blood sugar can develop serious or mortal complications, including heart disease, stroke, kidney problems, nerve damage and view problems.
Taking medications, making lifestyle (for example, diet, exercises, quitting smoking) and regularly verifying your blood sugar can help you control your diabetes and improve your health.This therapy can also reduce its possibilities of suffering a heart attack, stroke or other complications related to diabetes such as renal deficiency, nerve damage (numbness, legs or cold feet, decrease in sexual capacity in men and women), problems of theView, including damage or loss of gum view or disease.Your doctor and other medical care providers will talk to you about the best way to control your diabetes.
How should this medication be used?
The presentation of canagliflozine is on tablets to be administered orally.It is usually taken once a day with breakfast or the first main meal of the day.Take the Canagliflozine at approximately at the same time every day.Follow the instructions that are on the label of your medical recipe and ask your doctor or pharmacist to explain any part that you do not understand.Take Canagaglozine exactly as indicated.Do not take more or less amount of the medication or take it more frequently than your doctor's recipe indicates.
It is possible that your doctor tells you to start with a low dose of canagliflozine and gradually increase the dose.
Canagliflozine controls type 2 diabetes but not the cure.Continue to take canagliflozine even if you feel good.Do not stop taking the canagliflozine without talking to your doctor.
Your doctor or pharmacist will give you the manufacturer's information sheet for the patient (medicine guide) when you start the treatment with canagliflozine and every time your medical recipe supplies again.Read the information carefully and ask your doctor or pharmacist if you have any questions.You can also visit the Food and Drug Administration website (Food and Drug Administration, FDA) ( Link to get the medication guide.
What other use is given to this medicine? Back to the beginning
This medicine can be prescribed for other uses;Ask for more information to your doctor or pharmacist.
What are the special precautions that I must follow?
BeforeTo take canagliflozine, report to your doctor or pharmacist if you are allergic to canagliflozine, any other medication or one of the ingredients containing canagliflozine tablets.Ask your pharmacist or check the medicine guide to obtain an ingredient list.
Report to your doctor and pharmacist what other medications with and without medical recipe, vitamins, nutritional supplements and herbal products are taking or planned to take.Be sure to mention any of the following: Inhibitors of the angiotensin converting enzyme (ECA) such as benazepril (lotnsin), captopril (capeten, enalapril (vasotec), fosinopril (monopril), lisinopril (prinivil, zestril), moexipril (univasc), PERANDOPRIL, (Aceon), Quinapril (ACCupril), Ramipril (Altace) and Taking it(Cozaar), Olmesartan (Benicar), Telmisartan (Micardis) and Valsartan (Diovan);(Rifadin, Rimactane, in Rifamate, in Rifater) and Ritonavir (Norvir, in Kaletra).
Report your doctor if you are receiving dialysis or have ever had kidney disease.Your doctor could tell you not to take canagliflozine.
Report your doctor if you are in a low sodium diet or have or have low blood pressure;candidiasis in the genital area or liver disease.If you are a man, inform your doctor if they never did the circumcision,
Report your doctor if you are pregnant, you plan to get pregnant or if you are breastfeeding.If you are pregnant while you take canagliflozina, call your doctor.
If you will undergo surgery, including dental surgery, inform your doctor or dentist that you are taking canagliflozine.
Alcohol can cause blood sugar change.Consult your doctor about the safe consumption of alcoholic beverages while taking canagliflozine.
You should know that Canagliflozine can cause vertigo, dizziness and fainting when she gets up very fast when she is lying.If you have this problem, call your doctor.This problem is more common when canagaglyzine begins to take for the first time.To avoid this problem, get out of the bed slowly, supporting your feet on the ground for a few minutes before getting up.
Ask your doctor what you should do if you get sick, develop an infection or fever, experience unusual stress or suffer an injury.These conditions can affect blood sugar and the amount of canagliflozine you may need.
What special diet should I follow while I take this medication?
Be sure to follow all the exercises and diet recommendations made by your doctor or nutritionist.It is important to eat a healthy diet and exercise regularly.
Follow your doctor's instructions about taking enough liquids during the day while taking this medication.
What do I have to do if I forget to take a dose?
Take the dose that he omitted as soon as he remembers.However, if it is almost time for the next dose, omits the dose that it lacked and continues with its regular dosing program.Do not take a double dose to compensate for the one that omitted.
What are the side effects that this medication could cause?
This medicine can cause changes in blood sugar.You must know the symptoms of a high and low sugar level in the blood and what you should do if you have these symptoms.
Canagliflozine can cause side effects.Report to yourDoctor if any of these symptoms is strong or does not disappear:
- Frequent urination, even during the night
- More thirst
- Constipation
Some side effects can be serious.If you present any of these symptoms, call your doctor immediately:
- Frequent, urgent urination, with burning or pain
- urine that is cloudy, red, pink or coffee
- Urine with strong smell
- Pelvic or rectal pain
(in women) Vaginal smell, white or yellowish vaginal secretion (can have lumps or appearance of cottage cheese) or vaginal itching
(in men) redness, itching or inflammation of the penis;Salppered in the penis, secretion with foul smell or skin pain around the penis
- Hormigueo in the arms and legs
- Loss of muscle tone
- weakness or heaviness of the legs
- confusion
- Lack of energy
- Cold, gray skin
- Irregular or slow heart rate
If you experience any of the following symptoms, stop taking canagliflozine and call your doctor immediately or look for emergency medical treatment:
- Salpt
- Urticaria
- Itching
- Difficulty breathing or swallowing
- Inflammation of the face, throat, tongue, lips, eyes, hands, feet, ankles or lower legs
- Ronquera
Canagliflozine can cause other side effects.Call your doctor if you have an unusual problem while taking this medication.
If you develop a serious side effect, you or your doctor can send a report to the Disclosure of Adverse Effects 'Medwatch' of the Food and Medicines Administration (FDA) on the Internet page [ Link or by phone at 1-800-332-1088.
How should I store or discard this medication?
Keep this medicine in the original container, tightly closed and beyond the reach of children.Store it at room temperature and far from excess heat and humidity (not in the bathroom).Discard any medication that is defeated or you no longer need.Talk to the pharmacist on the proper way to discard the medication.
What should I do in case of an overdose?
In case of overdose, call the local poisoning control office at 1-800-222-1222.If the victim is unconscious, or does not breathe, call 911 immediately.
What other important information should you know?
Assist all appointments with your doctor and in the laboratory.Blood sugar levels must be controlled regularly to determine your response to canagliflozine.Your doctor will order other laboratory tests, including glycosilated hemoglobin (HBA1C) to evaluate your Canagliflozine response.Your doctor will also tell you how to review your response to this medication by measuring blood sugar levels at home.Follow these instructions carefully.
Before performing a laboratory test, report to the medical and laboratory staff who are taking canagliflozine.Due to the way in which this medication works, it is possible that the urine test positive for glucose.
You should always use a diabetic identification bracelet to be sure to receive adequate treatment in case of emergency.
Do not let anyone else take your medication.Take your pharmacist any question about how to put your medical recipe again.
It is important that you maintain a written list of all the medicines that you are taking, including the ones you received with a medical recipe and those you bought without a recipe, including vitamins and diet supplements.You must have the list every time you visit your doctor or when you are admitted to a hospital.It is also important information in emergency cases.
Commercial brands: Invokana®
DocumentUpdated - 03/15/2014