create an intelligent insulin patch to end diabetes
The secret patch a dose of insulin when necessary.This will cause patients to have a better quality of life, and an amount greater than what your body needs, with its consequent benefits.
A small insulin patch, square and not bigger than a cent, could replace the injections for diabetics, according to a study published by the scientific journal "Proceedings of the National Academy of Sciences" (PNAS).
The patch can detect the increases in blood sugar levels and secrete insulin doses in the bloodstream when necessary.In addition, the objective of its creators is that you only have to change every day, to make the treatment more bearable.
Until now, the patch has only been tested in mice with type 1 diabetes, but, according to their designers, the results of this study are "promising" of their success in humans.In fact, they argue that the stabilizer effects of the patch could be even more durable in humans since they have more insulin sensitivity than mice."We have designed a diabetes patch that works fast, it is easy to use and is made of non -toxic and biocompatible material," said Zhen Gu, one of the study authors, prepared by scientists from the University of North Carolina and the Universityof the state of North Carolina, in the United States.
"The system can be personalized depending on the weight of the diabetic person and its insulin sensitivity, so we can make this smart patch even more intelligent," added the researcher.The study authors underline that current insulin injections imply a process for the patient that is "painful and imprecise.""Injecting an incorrect amount of medication can lead to significant complications such as blindness and limb amputations, or more disastrous consequences such as diabetic coma or death," said John Bus, another of the authors of the investigation.
According to the study, diabetes affects more than 387 million people worldwide, and the figure is expected to increase up to 592 million by 2035.
Padre de Andrés, 17 años. Debut: septiembre de 2011. Levemir (30ud. mañana y 24ud. noche) y Novorapid (en desayuno, comida, merienda y cena 40ud aprox - 24HC/día). Medidor continuo DEXCOM G4 desde julio 2014 Hemo: 6.2 (Sept. 2013), 7.0 (Dic. 2013), 6.9 (Marzo 2014), 6,6 (Junio 2014), 6,7 (Sept. 2014), 7,0 (Dic. 2014), 7,7 (Mar 2015), 6,9 (Jul. 2015), 7,0 (Sept 2015), 7,4 (Dic 2015), 6,8 (Mar 2016), 6,6 (Julio 2016), 6,8 (Octubre2016)... 7,0 (Mar 2018)
On the one hand badly, because the head of the news is quite biased, it seems that this will cure diabetes, and to which you read the detail, nor joke! But well ... they are things of journalists ... byAnother side, because it seems that the thing is advancing, although it still lacks time, in fact, diving through the forum, you will see that this issue was already news a couple of years ago, and the forecast of departure to the market then was the2017.
You are right, some other forero said it, if we were mice, we would be cured !!!: D: D: D: D.
Even so, we must not lose hope, I follow these issues with interest because they are giving step, and that is much better than not advancing anything, hopefully the day we see news like this but instead of mice but instead of mice but instead of with miceWith people !!
I think that pharmaceutical laboratories are not interested that diabetes and many other diseases disappear.They make us gas light with this news!: (((
In the newspaper the world explains the news in much more depth. Link I copy the pieces that are not explained in the first post ...
how it works
The patch, not bigger than a small coin, is covered with hundreds of microagujas that contain enzymes that detect glucose and insulin vesicles, a system that mimics the beta cells of the pancreas.The operation is due to the presence of two substances: hyaluronic acid-very used in the cosmetic industry-and 2-nitroimidazole, an organic compound.The fusion of both substances resulted in a molecule that is at one end is hydrophilic and the one in another hydrophobic, whose structure is similar to that of bubbles, 100 times smaller than the width of human hair.In each of these vesicles a solid insulin and enzyme core designed for glucose detection was inserted.
Thus, blood glucose levels increase, vesicles absorb excess sugar and enzymes that are inside transform glucose into gluconic acid consuming all oxygen.The hypoxia situation causes hydrophobic molecules to become hydrophilic, giving rise to a rapid decrease in vesicles that in turn send insulin to the bloodstream.
Both glucose detection and insulin release is done through small microagujas arranged on a silicon sheet.When placing the sheet on the skin, microagujas penetrate it by contacting the capillaries ...
Problems
... José Ramón Calle, from the San Carlos Clinical Hospital of Madrid, an adventure that this system could stumble with the same problems that insulin pumps and glucose sensors are currently."These sensors measure glucose in the interstitial fluid and not in the blood and that generates a small time gap on the patient's situation, especially in certain situations such as a meal or while exercising. In addition, the insulin that is managed notIt is as fast as the one generated by the body of non -diabetic people and does not go to the portal system or the liver, which decreases the reliability of the treatment.
