Identify because gastric bypass can completely reverse type 2 diabetes

fer's profile photo   05/02/2015 8:46 p.m.

Scientific researchers at Boston Children's Hospital identified a protein called GLU-1 as responsible for the bariatric surgery known as Gastric and Roux (RYGB) by, in many cases, "heal" type 2 diabetesPrevious scientific studies showed that gastric bypass could completely reverse type 2 diabetes in 27% of cases for a period of 5 years or more.

Previous scientific studies conducted by researchers at Cleveland Clinic in OHIO showed that gastric bypass surgery “and Roux” (RyGB) completedl or minors without using any type of diabetes treatment), in 31% of cases due to a period of 1 year and in 27% of cases due to 5 years or more, as reported by the DR.Stacy Brethauer who led that retrospective study.

But why can the gastric bypass reverse type 2 diabetes?

To respond to this, a group of researchers at Boston Children's Hospital in Massachusetts led by Dr. Nicholas Stylopoulos conducted a scientific study using laboratory rats.

In 80% of cases, people with obesity and type 2 diabetes stop requiring medicines for diabetes shortly after gastric bypass and in many cases this happens before they are discharged from the hospital.For this reason, the researchers thought that the "sudden cure" of diabetes, in these cases, could be due to hormonal changes and fat cells and muscles, caused by gastric bypass.

However, this study revealed that the small intestine plays a very important and until now unknown role, since it modifies the way in which it processes glucose, as the researchers could verify after the gastric bypass that made the rats.

"We had not previously considered the small intestine as an important organ in the use of glucose, but we found that this is exactly what happens after surgery," said Dr. Stylopoulus.

The researchers enhanced a series of rats experiments showing how the "Roux Limb" or Roux piece (in the small intestine) was exposed to undigested nutrients.This prompted the metabolism of glucose "reprogramming" so that the small intestine became an important organ in the expulsion of glucose excess of the bloodstream, after subjecting the laboratory rats to a gastric and roux bypass* (* (*in memory of Dr. Philibart Roux, French surgeon pioneer of the union in and in the intestines).

The increase in the levels of intestinal glucose that rats had after gastric bypass seems to have been greater due to the regulation of the 1 glucose transporting protein (Glu-1).

"The reprogramming of glucose metabolism in the small intestine can be the explanation of why type 2 diabetes can disappear suddenly and completely, in some cases, after gastric bypass surgery," said Dr. Nima Saeidi, PHD,Study spokesman, in a report published in the magazine "Science" in July of this year.

New medications can be developed after these findings

The eyes of the pharmaceutical industry will be very attentive to the conclusions of this study, since if these results are confirmed, they will begin to develop new medications that simulate the beneficial effects offered by gastric bypass without the need for interested patients to have to undergoThis surgery.

“Promoting the increase in intestinal glucose and its subsequent use within the intestine can offer an opportunity for expulsion of excess ofglucose of the entire organism that will undoubtedly improve glycemic control in people with type 2 diabetes, "said Dr. Saeidi and concluded saying" to take advantage of the changes that occur in intestinal metabolism after gastric bypass and Roux (RyGB) can represent aApproach to replace this surgery for other equal treatments as effective but less invasive. ”

Undoubtedly, scientific research advances by leaps and bounds in search that the population with worldwide diabetes can control their glucose and hemoglobin A1C levels in a more comfortable, effective, simple and safe way and thus offer all a better quality oflife.Therefore, in diabetes a day we will be attentive to this and other research to keep them up to date with these scientific advances and thus can enjoy a healthier, productive life, happy and free of complications.

By Joe Cardozo

fer's profile photo
fer
05/02/2015 8:46 p.m.

@fer - Diabetes Tipo 1 desde 1.998 | FreeStyle Libre 3 | Ypsomed mylife YpsoPump + CamAPS FX | Sin complicaciones. Miembro del equipo de moderación del foro.
Co-Autor de Vivir con Diabetes: El poder de la comunidad online, parte de los ingresos se destinan a financiar el foro de diabetes y mantener la comunidad online activa.

  

This seems much better idea than the complicated operation ...
Bravo, Bravo ... !!!

nina45's profile photo
nina45
05/02/2015 9:05 p.m.

Diabetica tipo II desde Diciembre de 2012 pero descendiente de diabéticos desde nacimiento
Medicacion: metformina de 850 gr mañana, mediodia y noche.
Ultima glicosila 6
Lema: "If you want a positive life, spent time with positive people!"

  

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