A drug for diabetes, linked to 300 deaths

A drug for diabetes, linked to 300 deaths

An American study concludes that Avandia raises the risk of heart attacks

A prescribed medication for patients with type 2 diabetes, marketed with the name of Avandia, has caused at least 300 deaths due to heart failure in three months to the people who consumed it.This is denounced by a report prepared by the administration of drugs and food (FDA), of the United States, and was released yesterday by The New York Times.This drug is also marketed in Spain with the same name.According to the results of that work, FDA scientists David Graham and Kate Gelperin have recommended the withdrawal of the Avandia market.The report indicates that this drug, which contains the active substance Rosiglitazona, is linked to the death of 304 people during the last quarter of last year, according to the American newspaper, which reveals that if each diabetic had been administered a similar similar drugcalled acts, about 500 heart attacks and about 300 cases of heart strikes would have been avoided every month, because Avandia, he says.You can damage your heart.

Curiously, the FDA approved that Avandia was marketed in the USA ...

Don't your own internal methods question?: Shock:

No comments, it seems very strong

Nine out of 10 scientists who supported the Avandia drug, linked to the laboratory
Most authors did not reveal their relationship with the pharmacist

GSK manufacturer headquarters in London.(Photo: Reuters)
Updated Friday 03/19/2010 13:12 (CET)
Reuters |Elmundo.es
London |MADRID.- Since a study related in 2007 the drug addiction drug with an increased risk of heart attacks, the controversial medication has not ceased to be in the mouth of the medical community.The last data about this antidiabetic appears in the last issue of the magazine 'British Medical Journal', which reveals that nine out of ten scientists who were in favor of Avandia had economic links with the manufacturer laboratory, the British Glaxosmithkline (GSK).

The drug helps diabetics to control their blood sugar levels, but some works have indicated that it contributes to an increase in heart attacks in some people.In fact, there is currently a debate on whether it is convenient to withdraw it from the market due to the complications observed, although the British regulatory body continues to recommend its use.

Researchers at the Mayo Clinic, Minnesota (USA), a scientific organization that does not depend on commercial sponsorships, analyzed 202 articles published in scientific journals, including editorials and letters, which commented on the risk of heart attacks linked to the use of Avandia since 2007.According to this analysis, 94% of the authors who demonstrated in favor of the product had some type of economic link with pharmaceutical companies involved in the treatment of diabetes and 87% with the British manufacturer GSK, specifically.

On the contrary, most scientists who expressed critical opinions towards Avandia had no conflicts of interest.

Likewise, 25 of 29 articles in which a rival drug, Atos, from the American Eli Lilly laboratory was recommended, to replace Avandia, they also had economic ties with the latter.

For Mohammed Murak, a medical professor who directed the study, even more serious is the fact that very few scientists had revealed their conflicts of interest by recommending one or another medication.This expert points out that it would be advisable to withdraw municipal advance.However, a manufacturer spokesman recalls that seven tests carried out since 2007 had not demonstrated any increase in cardiovascular episodes as a result of their use.

The work published by 'British Medical Journal' concludes that there is a clear and strong link between the orientation and the point of view expressed by researchers and the existence of conflicts of interest with pharmaceutical companies."This finding underlines the need to improve this aspect and make clear the links of each one to increase confidence in scientific research."

For me this "discovery" is still inexplicable ...
In 2007, the Spanish Medication Agency already made the issue clear:

Guerrilla war between the pharmaceutical industry?:-/