The 'glycation gap' could be "diabetes thermometer"

fer's profile photo   01/28/2011 1:37 p.m.

CIBEROBN researchers have conducted a study that demonstrates that the one known as 'glycation gap' could be used as a "thermometer" to control diabetes and know the chances of vascular diseases, nephropathy, retinopathy or neuropathy.

Glycation is the spontaneous union of glucose to different physiological proteins.For its part, the glycation gap refers to the different degree of glycation in diabetes patients with similar blood glucose levels.

"There are people with high glucose who spend the years and practically have no complications, and vice versa, others who control their diabetes and are fatal," explains the Cyberbon researcher and main author of the study, Santiago Rodríguez Segade.

The study, which is published in the last issue of 'Clinical Chemistry', points out that type 2 diabetics that are high glycadores are more likely to suffer vascular diseases, nephropathy, retinopathy or neuropathy.

Therefore, these data "support" the hypothesis of the so -called 'glycation gap', which acts as a "thermometer" according to which for the same level of medium blood glucose there are patients who are low, moderate and high glycadores, who canconsequence develop different degrees of microvascular complications.

To carry out the research, the team has analyzed the data of a cohort carried out for 14 years on 2,314 patients with type 2 diabetes. In the follow -up, patients were valued to diabetic nephropathy according to the subjects had a low glycation level, moderate or high.

To calculate the 'glycation gap', the authors used glyd hemoglobin tests (indicatedthe previous two weeks and indicate extracellular glycation).

"The clinician can handle each patient does he know if he is high or low glycador and can better adjust the dose in each case," says Santiago Rodríguez, who warns that this test does not remain important to the "usual" test ofglyd hemoglobin, but provides "additional and complementary information."

fer's profile photo
fer
01/28/2011 1:37 p.m.

@fer - Diabetes Tipo 1 desde 1.998 | FreeStyle Libre 3 | Ypsomed mylife YpsoPump + CamAPS FX | Sin complicaciones. Miembro del equipo de moderación del foro.
Co-Autor de Vivir con Diabetes: El poder de la comunidad online, parte de los ingresos se destinan a financiar el foro de diabetes y mantener la comunidad online activa.

  

It must be a new analysis that is not yet done, but it is interesting.And even more if they will find a medication that decreases or avoids glycation.I guess they will be investigating in that.

Regina's profile photo
Regina
01/18/2015 7:04 p.m.

Hija de 35 años , diabética desde los 5. Glico: normalmente de 6 , pero 6,7 la última ( 6,2 marcaba el Free)
Fiasp: 4- 4- 3 Toujeo: 20

  

delaforce said:
Google fast in 2009 there was already study and treatment: aminoguanidine, dptc and alangebrium.http: //www.medigraphic.com/pdfs/revinvcli/nn-2009/nn096J.pdf

Come on, the same studies are repeating randomly and as people do not remember again.

I know they don't want to find the cure but at least they could hide it better.:(

Sherpa41's profile photo
Sherpa41
01/19/2015 4:16 p.m.

En 1922 descubrieron la insulina, en 1930 la insulina lenta. ¿Que c*** han hecho desde entonces?

  

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