Well, the O´sullivan reflects an insulin state of resistance.That next to high levels of cholesterol and hypertension is included in what is called metabolic syndrome (this denomination is something controversial since its pathophysiopathology is not well defined or what is the same the form/mechanism in which the symptoms are linked).
Metabolic syndrome has been related to the metabolic activity of visceral fat that would have counterinsular functions (that is, it opposes insulin promoting an insulin state of resistance and therefore a "prediabetes" or "situation of more risk of suffering from diabetes").
Metabolic syndrome, as I explained is a situation of insulin resistance, the pancreas, to compensate for this situation, "overdue" secreting more insulin than another person who does not have metabolic syndrome would need.Insulin, in addition to its hypoglycemic action has other effects (for example it influences the maturation of ovarian follicles in women, and increases cholesterol).The presence of high tension figures is also characteristic of this syndrome.
The diagnostic criteria are:
Increased abdominal perimeter (& GT; 102 cm in men and 88 in women)
Triglycerides & GT;150
HDL & LT cholesterol;40 in y & lt; 50 in women
Ta greater than 135/85
Fasting glycemia & GT;110
(Check if you meet the criteria).
As it seems that the main base of the syndrome is the accumulation of visceral fat (which can be "measured" through the abdominal perimeter) and as a consequence of insulin resistance the treatment can be directed to both factors (lifestyles/diet/exerciseto lose weight and reduce abdominal perimeter) and drugs that reduce insulin resistance (basically metformin) in addition to treating each symptom separately (hypertension and hypercholesterolemia).There are other alternatives such as Rimonabant (accompany) but clinical efficacy is doubtful, it is very expensive and the insurance does not happen, and this is important, no therapeutic combination has proven better than physical exercise.
In short, you are in a situation that requires several drugs to preserve your cardiovascular health (namely an insulin resistance reducing agent such as metformin, a hypolipemit, a hypotensor and an antiaggregant as aspirin) but if you manage to reduce abdominal perimeter (assuming it really isgreater than 95-102 cm) it is possible that you can do without any of those pills (which is why I encourage you 3-5 hours of weekly aerobic exercise).
Regarding that your cholesterol is worse controlled with fluvastatin is normal, atorvastatin is more powerful.In this regard, tell you that there are two functional foods (a functional food is one that has some property in addition to the nutritious properly, such as lowering cholesterol).I mean soy lecithin (low cholesterol) and linen (low cholesterol and triglycerides) that you can buy in granulate and add in small quantities to salads or yogurts (1 tablespoon a day of every 1, since they are omega 3 oils and6 And as you know these fats are very beneficial in small quantities but they are still fat (drinking some olive oil per day is good, drinking 1 glass of olive oil per day, drinking 1 small glass of red wine to theday it can be good, take 1L a day not).
Anyway, I hope you serve the information.All the best
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