Possible cure for type 1 diabetes?

fer's profile photo   12/19/2008 6:24 a.m.

Recently I have read the article that I copy below, it is really hopeful and it would be fantastic if you could really reach the cure.What do you think? Do you think this cure can really get?

medications that could prevent or reverse type 1 diabetes
Introduction
There are 2 medications that are used successfully to treat cancer, which have thrown promising results so that type 1 diabetes can be prevented and even reverse in those already diagnosed.

San Francisco, CA.November 26, 2008- With the use of two medications to treat cancer, a team of scientific researchers from the University of California in San Francisco managed to prevent the diagnosis of type 1 diabetes in laboratory mice with high predisposition to develop it and also could reverse itin 80 % of mice that already had type 1 diabetes.

content
These medications known as Gleevec (Imatinib) and Sutent.1.

Both Gleevec and Sutent block the kinase tyrosins, which are enzymes receiving growth factor derived from platelets (PDGFR) that regulate the growth and division of cells and are also related to the inflammation process and the functioning of the immune system.

Many researchers agree that in addition, the kinase tyrosins can facilitate the development of cancer and other immumological diseases, so these researchers assumed that they also played a role determining in the attack of immune system cells to beta cells (insulin producers) that is what causes the appearance of type 1 diabetes.

How was this important study conducted?
Dr. Jeffrey Bluestone, spokesman for the team of researchers declared that he and his colleagues wondered if these medications could also block some of the kinase thyroxins that they supposed they were directly related to the development of type 1 diabetes and immediately began to investigate them.

The idea was to test these medications in mice with high predisposition to develop type 1 diabetes, which as everyone knows, is an immune disease.The results were surprising since these medicines prevented these mice from developing type 1 diabetes.

One more step in this study consisted of the use of these medications in mice that already had type 1 diabetes and the results in this regard were even more promising, since 80% of these mice presented normal blood glucose levels, thenFrom only 8 to 10 weeks of treatment.

This showed that the researchers were successful in their hypothesis that these medications could block the receptors of a kinase tyrosine of which until that time it was unknown that it was closely involved in the development of type 1 diabetes.

Dr. Jeffrey Bluestone, concluded saying "the fact that mice treated with these medications maintained normal blood glucose levels for some time after the treatment was stopped, indicates that both the Gleevec (Imatinib) and the Sutent (Sunitinib) could have rescheduled their immunological systems permanently. "

For her Pate, Dr. Teodora Staeva Ph.D.Who is the Director of Immunology of the Youth Research Foundation of Diabetes (JDRF) said: "The results of this study suggest that kinase inhibitors can provide new ones in theType 1 diabetes treatment and other immune character diseases "

A hope to the future
Type 1 diabetes, also known as insulin -dependent diabetes and youth diabetes, sinceWhat in this type of diabetes does not produce insulin and people with type 1 diabetes depend only on the use of exogenous insulin for treatment, unlike people with type 2 diabetes who have an extensive variety of medications and therapiesof control at your disposal.Therefore, this important study is still much greater relevance and without a doubt, it opens an immense window of optimism and hopes to all those with type 1 diabetes.

We feel very optimistic and hopeful that scientific research worldwide will continue to advance successfully towards the definitive cure of diabetes.While that day comes, we will continue in our fight to offer all those people with diabetes, the necessary tools so that they can enjoy a healthier, productive, happy and free life life.

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fer
12/19/2008 6:24 a.m.

@fer - Diabetes Tipo 1 desde 1.998 | FreeStyle Libre 3 | Ypsomed mylife YpsoPump + CamAPS FX | Sin complicaciones. Miembro del equipo de moderación del foro.
Co-Autor de Vivir con Diabetes: El poder de la comunidad online, parte de los ingresos se destinan a financiar el foro de diabetes y mantener la comunidad online activa.

  

Very interesting, I think it is the most successful line of research, in terms of type1 diabetes.

Problem: How do you know the predisposition to suffer from type1 diabetes?
Is there any genetic test that ensures it at 99%?

Are the kinases and the causes that the immune mechanism has loaded my beta cells?: Shock:
Until now this had not been shown ... if true, it is the best advance since the discovery of insulin.

It is also true that when he says "for some time they kept their figures of normal glycemia" ...
How long? What happened later ...?

Bernat Soria's "investigations" always come to mind that ended some beautiful neoplasms in the mice:-/

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DiabetesForo
12/19/2008 4:32 p.m.
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I have searched for the definition of neoplasia and I was left of stone ... bad, bad ... I copy it:

Neoplasia (new growth in Greek) is the abnormal proliferation process of cells in a tissue or organ that leads to the formation of a neoplasm.

A neoplasm that forms a differentiated mass is called tumor.Other neoplasms may not form tumor, such as intraepithelial cervical neoplasia and leukemia.

A neoplasm can be benign, or potential or clearly evil.Among the malignant neoplasms we find many types of cancer.

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fer
12/22/2008 3:26 p.m.

@fer - Diabetes Tipo 1 desde 1.998 | FreeStyle Libre 3 | Ypsomed mylife YpsoPump + CamAPS FX | Sin complicaciones. Miembro del equipo de moderación del foro.
Co-Autor de Vivir con Diabetes: El poder de la comunidad online, parte de los ingresos se destinan a financiar el foro de diabetes y mantener la comunidad online activa.

  

I have searched for the definition of neoplasia and I was left of stone ... bad, bad ... I copy it:

Neoplasia (new growth in Greek) is the abnormal proliferation process of cells in a tissue or organ that leads to the formation of a neoplasm.

A neoplasm that forms a differentiated mass is called tumor.Other neoplasms may not form tumor, such as intraepithelial cervical neoplasia and leukemia.

A neoplasm can be benign, or potential or clearly evil.Among the malignant neoplasms we find many types of cancer.

Bernat Soria's collaborators tell how the mice used in their experiments, 15 days after carrying out the experiment they look unbeatable and healthy which Pixie and Dixie.

At 30 days they were terminal patients with generalized metastasis.

B. Said sacrificed animals at 15 days.

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DiabetesForo
12/23/2008 12:37 a.m.
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Better than Bernat Soria staying still, who already scares.

Health

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DiabetesForo
12/23/2008 11:13 a.m.
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This news is entirely hopeful, but why does not have the news of such magnitude the media impact that is supposed to have?
Any other bullshit without major importance are taken in the news around the world and this, which seems to me something magnificent I have to read in this forum.
I am giving me the impression that there is not too interest in finding a definitive solction for all these VIP clients of the laboratories that show off.
Hopefully this wrong, that nobody thinks about the economic benefit and that they only want to avoid the suffering of the millions of children who live slaves of other people's insulins.
: Twisted :: Twisted:
MERRY CHRISTMAS ;)

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DiabetesForo
12/23/2008 7:11 p.m.
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