In the European Congress on Obesity in Venice, study has been shared and has also been published in the 'International Journal of Obesity'.This study, conducted by the Karolinska Huddinge University Hospital in Sweden, explains why type 2 diabetes seems to be more common in men than in women.
For years, studies have observed that men develop type 2 diabetes at an earlier age and with a lower weight compared to women.A hypothesis that this study has explored deeply is the difference in how adipose tissue, or fatty tissue, of each sex responds to insulin.
The research led by Dr. Daniel P. Andersson has shown that adipose tissue is the main organ of excess energy storage in the form of lipids or triglycerides.When there is an excess of energy, insulin normally helps reduce the decomposition of these triglycerides and increases their storage, but in people with insulin resistance, this process does not work correctly.
The study results indicate that, in conditions of obesity, men have greater insulin resistance in their adipose tissue compared to women.This was even evident when measuring the amount of insulin necessary to prevent the decomposition of triglycerides in fatty acids;In men, an insulin concentration was required ten times greater than in women to achieve the same effect.
This difference could explain why men tend to have higher levels of free fatty acids in the blood, which can negatively affect other organs such as liver, muscles and pancreas, further increasing insulin resistance andRisk of developing type 2 diabetes.
This finding is crucial because it underlines the importance of considering sex differences in the treatment and management of type 2 diabetes, especially in people with obesity.Understanding these differences allows us to approach more personalized and effective treatments to prevent and manage this condition.
I hope this information is interesting and help to better understand the complexities of type 2 diabetes.
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