The authors of the University of Leicester and the School of Hygiene and Tropical Medicine of London (United Kingdom) conclude that these results not only underline the growing load of cancer in people with type 2 diabetes, especially in older people, but also “highlight theNeed to prioritize prevention, research and early detection and cancer management in this population, especially for some tumors such as colorectal cancer, pancreas, liver and endometrium ».
Directed by suping ling, the work also showed an increase in breast cancer mortality rates by 4.1 % per year, in younger women with type 2 diabetes, during the study period of 20 years of 1998 to2018.
The accumulated epidemiological evidence has shown that there is a higher risk of incidence and mortality for some types of cancer in people with type 2 diabetes, with prolonged exposure for the purposes of increasing blood sugar and insulin levels, being the resistance toInsulin and chronic inflammation possible underlying biological mechanisms.
It has also been shown that there is a causal relationship between type 2 diabetes and pancreatic cancer, liver and endometrium.
In this study, the authors used a cohort of people 35 years of age or older who had freshly diagnosed diabetes and analyzed trends in mortality rates for all causes, for all types of cancer and specific cancer by age, age,Sex, ethnicity, socioeconomic level, obesity and smoking.They also calculated standardized mortality rates by comparing mortality rates in people with type 2 diabetes with the general population.
The study included 137,804 people with newly diagnosed type 2 diabetes with a medium tracking of 8.4 years.
The authors found a decrease in cardiovascular mortality in older groups that, in their opinion, has occurred thanks to successful cardiovascular prevention and treatment in recent decades.
This makes people live more and have a greater probability of experiencing other diseases and, therefore, dying for other causes.However, the detection of diabetes, better control of diabetes and their complications, early detection of cancer and the improvement of cancer treatments seem to have benefited younger people with type 2 diabetes in the same way asThey have done it in the general population.
The prevention of cardiovascular diseases has been, and is still considered, a priority in people with diabetes.But experts say that their results show that cancer may have surpassed cardiovascular disease as the main cause of death in people with type 2 diabetes.
Therefore, they write, «cancer prevention strategies deserve at least one level of attention similar to the prevention of cardiovascular diseases, especially in older people and for some types of cancer, such as liver, colorectal and pancreatic cancer».
