Type 2 diabetes is typically considered a chronic disease, which as it progresses, entails the need to carry a healthy diet, exercise and an increasingly complex combination of medications to control it.
Pathology occurs when an individual does not produce enough insulin-the hormone that allows cells to absorb blood glucose-or the pancreas is not manufacturing insulin as efficiently as it should, resulting in blood sugarsThey accumulate in the body and the cells do not receive the energy they need.
Type 2 diabetes can be reversed with an intensive medical treatment with oral drugs, insulin and lifestyle therapies, according to a study published in 'Journal of Clinical Endocrinology & AMP;Metabolism 'of American endocrine society.
"Through the use of a combination of oral medications, insulin and lifestyle treatments to treat patients intensely for two to four months, we find that up to 40 percent of the participants were able to remain in remission three months laterTo stop taking diabetes medicines, "highlights the first author of the study, Natalia Mcinnes, from the University of McMaster and 'Hamilton Health Sciences', in Hamilton, Ontario, Canada."The findings support the idea that type 2 diabetes can be reversed, at least in the short term, not only with bariatric surgery, but with medical approaches," he adds.
To study ways to place type 2 diabetes in remission, researchers randomly divided 83 individuals with the disease into three study groups.Two of the groups received an intensive metabolic intervention where a personalized exercise plan was provided and a food plan that reduced their daily calorie consumption in between 500 and 750 calories per day was indicated.
These study participants gathered regularly with a nurse and a nutritionist to monitor their progress and received oral medications and insulin at bedtime to rigorously control their blood glucose levels.One group underwent the intervention for eight weeks, while the other was treated intensely for 16 weeks.After the intervention, the individuals of both groups stopped taking diabetes medications and were encouraged to continue the changes in their lifestyle.
Total or partial remission eight weeks after the intervention
The two intervention groups were compared with a control group of individuals with type 2 diabetes. The participants in this group received standard advice on blood sugar management from their usual medical care provider during the duration of the trial and received standard advice onlifestyle.The members of the three groups received habitual attention from diabetes if they experienced a relapse of diabetes.
The average blood glucose levels of the participants of the last two to three months were measured using an HBA1C blood analysis at eight, 20, 28 and 52 weeks to assess how their sugar in the blood was well controlled.Oral glucose tolerance tests were also performed.
Three months after completing the intervention, 11 out of 27 individuals of the 16 -week intervention group complied with the HBA1C criteria for the total or partial remission of diabetes, compared to four of 28 individuals in the control group.Three months after finishing the intervention of eight weeks, six of 28 individuals in that group met the same criteria for the complete or partial remission of diabetes.
"Research could change the paradigm ofTreatment of diabetes from simply controlling glucose to an approach to induce remission and then control any relapse sign in patients-mcinnes plan.The idea of reverse the disease is very attractive for people with diabetes, which motivates them to make significant changes in lifestyle and achieve normal glucose levels with the help of medications.This probably gives the pancreas a break and decreases fat reserves in the body, while improving insulin production and effectiveness. "
The main researcher of the trial, Hertzel C. Gerstein, of the McMaster University and 'Hamilton Health Sciences, "adds:" We choose to use metformin, caress and insulin basal glargine in this essay, since it has been shown that all these medications delay or preventThe development of type 2 diabetes. However, other drug combinations could lead to higher remission rates and must be systematically studied with respect to this result. "
Source: Madrid, 16 (Europa Press)