{'en': 'New evidence of the link between enterovirus and type 1 diabetes', 'es': 'Nuevas evidencias del vínculo entre enterovirus y diabetes tipo 1'} Image

New evidence of the link between enterovirus and type 1 diabetes

fer's profile photo   01/11/2017 10:54 a.m.

Children with type 1 diabetes have a greater incidence of enterovirus infections before experiencing autoimmune processes that lead to metabolic disease, according to a study that has been published in Diabetology.

Enterovirus have been linked to type 1 diabetes in studies that show a greater frequency of these blood viruses and the pancreas of diabetic individuals and positive autoantibodies.However, this association has not been appreciated in all works.

In the new study one of the broadest ones to date, a team led by Heikki Hyoty and Hanna Honkanen, from the University of Tampere (Finland), analyzed whether the presence of integer in feces was related to the appearance of autoimmunity against thepancreatic islets.This evaluation has been carried out within the framework of the prediction and prevention study of type 1 diabetes, with Finnish population.

difference between cases and controls

The researchers collected 1,673 fecal samples of 129 children who developed acting in front of the pancreatic islets and another 3.108 samples of 282 minors that served as controls.In all of them, the presence of Enterovirus RNA was investigated, which led to the diagnosis of 108 infections in the 129 children with autoimmunity and 169 in the 282 controls during the monitoring period, which is an average of 0.8 against 0,6 infections per child, respectively.This difference was also appreciated in the infections that occurred before the appearance of autoantibodies (0.6 compared to 0.4 infections per child).

The analyzes that were carried out later showed that the excess of infections that were appreciated in the children predisposed to the development of type 1 diabetes occurred more than 12 months before the first positive blood sample was obtained to autoantibodies.During that period of time, an average of 0.62 infections between these children were diagnosed, compared to 0.33 between the controls, which corresponds to 6.3 and 2.1 infections in the 10 years of follow -up.In other words: children with type 1 diabetes had triple infections than the rest.

The authors comment that their study reveals that enterovirus infections in the pediatric population "are associated with the appearance of autoantibodies in front of the pancreatic islets after approximately one year. This finding agrees with the previous observations of other prospective studies that suggest thatEnterovirus infections could play a role at the beginning of the beta cell deterioration process. "

On the other hand, they point out the interest of "exploring the possibility of creating a vaccine against these viruses in order to prevent type 1 diabetes."

fer's profile photo
fer
01/11/2017 10:54 a.m.

@fer - Diabetes Tipo 1 desde 1.998 | FreeStyle Libre 3 | Ypsomed mylife YpsoPump + CamAPS FX | Sin complicaciones. Miembro del equipo de moderación del foro.
Co-Autor de Vivir con Diabetes: El poder de la comunidad online, parte de los ingresos se destinan a financiar el foro de diabetes y mantener la comunidad online activa.

  

It seems quite interesting to know the real origin of the process that makes our body change the chip and "turn against us."

pike's profile photo
pike
01/12/2017 1:29 p.m.

DM1 desde 2015-Novorapid 2/2/2/2-Toujeo(en proceso)-Mañana
Glucosilada 4/2017: 7,2

  

I thought that this issue was already more advanced. The relationship between viruses and diabetes is known.

Regina's profile photo
Regina
01/12/2017 4:01 p.m.

Hija de 35 años , diabética desde los 5. Glico: normalmente de 6 , pero 6,7 la última ( 6,2 marcaba el Free)
Fiasp: 4- 4- 3 Toujeo: 20

  

@Regina I also thought that I was going to be more advanced ... but I still think that, on many occasions, we do not advance because we are a very good business for pharmacies, doctors and researchers.Well, thanks to us, we feed many families (since they are dedicated to "finding out" a solution for diabetes

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EuBeRiRo_24
01/12/2017 9:23 p.m.

Diabetes Tipo 1 desde Mayo de 1993.
Tresiba: 32 Ui a las 23:00h
Humalog Kwipen: de 2 a 5 Ui en cada (dependiendo de las cantidades de Hc y los niveles de glucosa)
HbA1c 7.4% ¡¡Alcanzando mi objetivo!!
Creciendo cada día y sin parar de luchar en este mundo llamado Diabetes
Del 92

  

Already .., but a vaccine for the prevention of type 1 would be a very good business.And we are still waiting ... I don't believe in that theory that we are not progressing because we are a business., the expenditure that the State supposes diabetes is very large.It is true that we depend on public research rather than private, but this is much more complicated than it may seem ..

Regina's profile photo
Regina
01/12/2017 9:52 p.m.

Hija de 35 años , diabética desde los 5. Glico: normalmente de 6 , pero 6,7 la última ( 6,2 marcaba el Free)
Fiasp: 4- 4- 3 Toujeo: 20

  

You have to tell the cure or vaccine is a business, but not as much as what there is now is a huge didión in profitability.You have to keep the diseases work on it but not to cure

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hoyos9
01/13/2017 1:05 a.m.
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