"It is known that in gestational diabetes, which occurs up to 10 -12% of pregnancies, there are higher levels of lipids and a greater proinflammatory environment, that is, a greater presence of inflammatory mediators than in normal pregnancy".This is explained by the gynecologist of the Puerta del Mar Fernando Bugatto Hospital, who has been awarded for a communication on this subject in the VIII International Symposium of Diabetes, Hypertension and Metabolic Syndrome in pregnancy, held in Berlin with the presence of 1,300 specialists of morefrom 70 countries.
In the award -winning work, the inflammatory component with blood circulation through the uterine arteries is related for the first time, which are responsible for contributing blood to the uterus and the placenta."The higher the levels of pro -inflammatory, lipid and blood glucose cytokines in the mother, worse is the circulation through these uterine arteries. This means that the best metabolic control and the reduction of lipids and the maternal inflammatory component could improve theCirculation through these arteries and help reduce some of the complications associated with diabetes, "he says.
This is the first time that in this Symposium-currently considered one of the most relevant meeting points among specialists within maternal-feetal medicine-awards are given to recognize the work of young researchers.For the Gaditano, it has been "a satisfaction" because it supposes "a reward for a job of many years, that we do it at the expense of our personal effort and our free time that we take to the family, since the care pressure we have isbig and there is little time to investigate. "It is also "an impulse to continue with this research work. You feel that you are contributing your grain of sand to the monitoring of pregnancy with gestational diabetes, to try to minimize all associated complications."
He states that he is only the visible head of a team in which there are several gynecologists and other health professionals, in addition to the biochemists who perform the laboratory work.He wants to highlight the research unit that the hospital has.He affirms that thanks to her, laboratory works can be carried out for the research carried out by him and other doctors in the center.
The award -winning work is part of the FIS (Health Research Fund) of the Carlos III Health Institute, of which Bugatto is the main researcher.He comments that in this project, using indirect calorimetry techniques, it is studied how maternal energy metabolism is changing throughout normal pregnancies and complicated pregnancies with obesity and gestational diabetes."We are obtaining interesting results that show that in women with gestational diabetes more fats (lipids) are used to obtain energy and that instead, placentas from these same pregnancies with gestational diabetes oxidize less fats than in cases of uncomplicated pregnanciesthat is, these placentas behave metabolically differently. "He adds that these results shed light on the metabolic alteration present in gestational diabetes, "although more studies are necessary that clarify the clinical meaning of these findings and if they are factors involved in the development of this pathology or only a consequence of gestational diabetesOnce it is presented. "
The results of this project have been published in international magazines with a high impact rate.
Fernando Bugatto studied medicine and did the doctorate in Cádiz and graduated in biochemistry at the Autonomous University of Madrid.Carried out the specialty of Obstetrics and Gynecology at the Puerta del Mar Hospital and research stays in theSt. Michael's Hospital of the University of Bristol, in the United Kingdom.Since the end of the specialty in 2006, he works at the Gaditano hospital, mainly commissioning, along with other gynecologists, the high -risk pregnancy consultation and that of diabetes and pregnancy (it is jointly with the UGC of Endocrinology).
He wants to highlight the importance of the existence of the joint unit of diabetes and pregnancy at the door of the sea, where he passes a gynecologist with an endocrine."That helps better control women with gestational diabetes and those who were diabetic before pregnancy," he concludes.