The insulin pill is close: was it ended up punctuating for diabetics?

Why isn't there still an insulin pill?

"Since the discovery of insulin 100 years ago, the development of an insulin pill has been a dream for diabetes researchers but, after decades of trying, it has been little successful," confesses Dr. Nicholas Kirk, of the Walterand Eliza Hall Institute (Wehi) of Melbourne and author of the study.

Until now, attempts to develop an insulin pill have failed because insulin is unstable and the body degrades it easily during digestion.

closer to an insulin pill

Wehi researchers in Melbourne have answered a question 100 years ago in diabetes research:

Can a molecule different from insulin have the same effect?

They have achieved it thanks to a state -of -the -art technology (cryiolectronic microscopy) that allows visualizing complex atomic detail molecules.In this way they have discovered that there is a concrete peptide that mimics the role of insulin."Actually what it does is activate the insulin receiver and keep it in an active position, such as two hands that grab some tweezers outside," explains Dr. Kirk.

The finding opens the door to develop a medication that could be taken orally to replace insulin, thus replacing the need to administer insulin injections.

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